READ THE WINNER OF 9 NATIONAL AND INTERNATIONAL BOOK AWARDS!"A marvelous book that's packed with knowledge, insight, and hope...he writes with admirable clarity."- Kirkus Reviews"This book bursts with good news." Booklife Reviews by Publisher's WeeklyStep inside the revolution in cancer medicine with Dr. Drew N. Kelner, Ph.D., a biochemist, cancer drug developer, and former scientific leader at the biopharmaceutical company Amgen, and learn how a century of groundbreaking discoveries in the biomedical sciences have ripped the lid off of cancer's black box of molecular secrets, revealing how tumors corrupt our biology to evade immunity and resist every therapeutic intervention we devise. Through vivid storytelling and with a knack for explaining complex scientific concepts in accessible language, readers meet the innovators behind “living drugs”—medicines made in biological systems, including engineered T cells (CAR-T cells), oncolytic viruses, and other seemingly magical medicines—that are changing the paradigm of cancer treatment from the traditional therapeutic triad of "cut, burn, and poison" that destroys both tumors and normal cells to targeted therapies that arrest tumor progression and metastasis and empower the immune system to seek out and destroy tumors. For some patients, these emerging “wonder drugs” are providing long-term remissions measured in years; for the most fortunate patients, even decades of remission have already been achieved. Taming Cancer presents a compelling and hopeful vision of a future when cancer will be managed as a chronic disease, much like rheumatoid arthritis and diabetes. For the most responsive patients, the eradication of cancer cells from the body—the long-sought cure for metastatic cancer—will become a reality for increasing numbers of patients.
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